Diffuse myocardial fibrosis in early forms of dilated cardiomyopathy: insights from T1 mapping cardiovascular magnetic resonance
نویسندگان
چکیده
Background The underlying myocardial injury in early forms of dilated cardiomyopathy (DCM) is unclear. Cardiovascular magnetic resonance (CMR) myocardial T1-mapping monitors the enlargement of the cardiac extra-cellular space and thus offers a non-invasive tool of quantitative measurement of myocardial fibrosis. We used T1mapping techniques to explore the hypothesis that diffuse myocardial fibrosis is related to DCM.
منابع مشابه
Non-invasive measurement of myocardial extracellular volume using T1 mapping as a novel biomarker of diffuse fibrosis in dilated cardiomyopathy
Background Diffuse myocardial fibrosis is frequently observed in histologies of dilated cardiomyopathy (DCM). T1-mapping techniques have the potential to measure fibrosis quantitatively and therefore provide novel cardiac magnetic resonance (CMR) insights into myocardial tissue characterization beyond the presently employed late gadolinium enhanced (LGE) techniques. Fibrosis results in expansio...
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the gadolinium-enhanced myocardium: adjustment for factors affecting interpatient comparison. Magn Reson Med 2011;65:1407–15. 21. Schneider CA,Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 yearsof image analysis. Nat Methods 2012;9:671–5. 22. Flett AS, Hayward MP, Ashworth MT, Hansen MS, Taylor AM, Elliott PM et al. Equilibrium contrast cardiovascular magnetic resonance for the measurement o...
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